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Description
STM32L452RCT6 Product Overview
STM32L452RCT6 is an Arm Cortex-M4 MCU at 80 MHz with FPU and ART Accelerator, LQFP-64. 256 KB Flash, 160 KB SRAM, USB 2.0 FS device (crystal-less), 12-bit ADC (16 ch), 12-bit DAC, two comparators, LP timers, RTC, 2×USART, 1×UART, 1×LPUART, 2×SPI/I2S, 4×I2C. Up to 52 x 5 V-tolerant I/Os. 1.71–3.6 V, -40–85 °C. Compared to the 48-pin L452CEU6, the 64-pin STM32L452RCT6 offers more I/Os and richer ADC channels while retaining the generous 160 KB SRAM and crystal-less USB, making it a more powerful ultra-low-power platform for battery-powered IoT nodes, portable instruments, and industrial sensors needing large data buffering, USB communication, and more pin connections.
STM32L452RCT6 Core Features
Core: The STM32L452RCT6 features an Arm Cortex-M4 core at 80 MHz, with FPU + ART Accelerator
Memory: The STM32L452RCT6 provides 256 KB Flash and 160 KB SRAM
USB: The STM32L452RCT6 integrates a USB 2.0 FS device (crystal-less)
Analog: 12-bit ADC (16 ch), 12-bit DAC, 2×Comparators
Connectivity: 2×USART, 1×UART, 1×LPUART, 2×SPI/I2S, 4×I2C
Timers: Advanced Timer, GP/LP Timers, RTC
I/Os: 52 (5 V-tolerant)
Package: LQFP-64
Temperature Range: -40°C to 85°C
STM32L452RCT6 Applications
IoT Sensor Nodes: Battery-powered wireless sensors and USB data acquisition modules can leverage the STM32L452RCT6's low power and connectivity
Portable Devices: Wearables, portable medical devices, and USB peripherals benefit from the STM32L452RCT6's compact integration
Industrial Metering: Water, gas, and electricity meters are ideal applications for the STM32L452RCT6
Consumer Electronics: Remote controls, e-labels, smart cards
Low-Power Systems Needing USB, Large RAM & More I/Os: Portable data loggers and handheld measurement devices can rely on the STM32L452RCT6
STM32L452RCT6 Key Advantages
256 KB Flash + 160 KB SRAM: The STM32L452RCT6 delivers class-leading large memory for complex data processing and buffering
Cortex-M4 + FPU + Ultra-Low Power: The STM32L452RCT6 achieves excellent DSP and floating-point performance while maintaining extremely low power consumption
Integrated Crystal-less USB: The STM32L452RCT6 enables USB communication without an external crystal, simplifying design and saving BOM
On-Chip DAC & Dual Comparators: The STM32L452RCT6 offers flexible analog output and signal threshold detection without external components
52 I/Os + LPUART + Multiple I2C: The STM32L452RCT6 provides rich peripheral connectivity for multi-sensor systems
5 V-tolerant I/Os: Enhanced system noise immunity, simplified external level-shifting circuitry
Full Ecosystem Compatibility: Easy development with STM32CubeIDE/HAL/LL libraries for the STM32L452RCT6
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FAQ
1. What is STM32L452RCT6?
STM32L452RCT6 is an ultra-low-power 32-bit MCU from STMicroelectronics' STM32L4 series, built around an Arm® Cortex®-M4 core with FPU and DSP instructions in an LQFP-64 package. Operating at 80 MHz, the STM32L452RCT6 provides 256 KB Flash and 160 KB SRAM, offering a cost-effective balance of generous on-chip RAM and moderate code storage for battery-powered devices.
2. What are the key specifications of STM32L452RCT6?
Core: Arm® Cortex®-M4, up to 80 MHz, 100 DMIPS with FPU and DSP
Memory: 256 KB Flash, 160 KB SRAM
Operating Voltage: 1.71 V to 3.6 V
Temperature Range: -40 °C to +85 °C (industrial grade)
I/O Count: up to 52
Package: LQFP-64 (10 mm × 10 mm)
3. Is the STM32L452RCT6 package easy to solder?
The STM32L452RCT6 comes in an LQFP-64 package measuring 10 mm × 10 mm with exposed 0.5 mm pitch leads. Drag-soldering the STM32L452RCT6 with a standard soldering iron and flux is straightforward—no hot-air station required—making it very suitable for hand assembly, small-batch production, and rapid prototyping.
4. What applications is STM32L452RCT6 suitable for?
With 160 KB of SRAM, a CAN 2.0B interface, USB OTG, and integrated operational amplifiers, the STM32L452RCT6 is ideal for cost-sensitive battery-powered devices needing generous data buffers, such as industrial sensor nodes, portable medical instruments, motor control drivers, smart home controllers, and IoT endpoints running an RTOS with multiple communication tasks.
5. What development tools support STM32L452RCT6?
ST provides free STM32CubeMX for graphical configuration and STM32CubeIDE as an integrated development environment for the STM32L452RCT6, along with the STM32CubeL4 firmware library. Debugging and programming are handled by ST-Link debuggers. The pin-compatible NUCLEO-L452RE board (with 512 KB Flash) serves as an excellent starting point for prototyping, requiring only minor adjustments for the 256 KB target.
6. What is the power consumption of the STM32L452RCT6 across its low-power modes?
Temperature Range: -40 °C to +85 °C
Ultra-low-power modes of the STM32L452RCT6:
Shutdown mode: ~33 nA (5 wake-up pins)
Standby mode: ~125 nA (5 wake-up pins), ~430 nA with RTC
Stop 2 mode: ~1.2 µA, ~1.4 µA with RTC
Run mode: ~100 µA/MHz (LDO mode)
7. What is the difference between STM32L452RCT6 and STM32L452RET6?
Both share the same package, pinout, peripherals, 80 MHz Cortex-M4 core, and 160 KB SRAM. The only difference is Flash capacity: the STM32L452RCT6 has 256 KB, while the RET6 has 512 KB. If your firmware fits within 256 KB, the STM32L452RCT6 is the more cost-effective option; otherwise, RET6 provides extra headroom for larger applications or future expansion.
8. What key peripheral interfaces does STM32L452RCT6 offer?
The STM32L452RCT6 provides the following key peripherals:
Communication: CAN 2.0B, I²C, SPI, UART/USART, USB OTG FS, SAI (I2S/PCM/PDM)
Analog: 12-bit 5 Msps ADC, 12-bit DAC, ultra-low-power comparators, operational amplifiers
Timers: 16-bit and 32-bit general-purpose timers, advanced motor-control timer
Others: Quad SPI interface, SDMMC interface
9. How does STM32L452RCT6 differ from STM32L476RCT6?
Both are LQFP-64 devices with an 80 MHz Cortex-M4 core and 256 KB Flash. The STM32L452RCT6 offers larger SRAM (160 KB vs 128 KB) and integrated operational amplifiers, but lacks the segment LCD driver found on the L476RCT6. If your design needs extra RAM and analog signal conditioning, the STM32L452RCT6 is the better choice; if you require a segment display, choose the L476.
10. What practical uses do the integrated operational amplifiers on the STM32L452RCT6 serve?
The on-chip operational amplifiers on the STM32L452RCT6 can amplify weak signals from sensors (such as current shunts or thermocouples) without external op-amp chips, simplifying the circuit and reducing BOM cost. They can be configured as followers, non-inverting amplifiers, or differential amplifiers, working together with the ADC to achieve high-precision signal acquisition—ideal for front-end signal conditioning in industrial sensing and portable medical devices.